Research in the field of anti-aging care is constantly evolving, with a proliferation of natural and topical alternatives to injections. You may have heard of botox-like active ingredients such as Spilanthes, retinol or resveratrol. But have you heard of Argireline? This active ingredient, from the peptide family and known as Acetyl Hexapeptide-8 in the INCI lists, is increasingly recognized for its anti-aging properties. Studies have shown that Argireline is effective in reducing wrinkles by targeting areas of muscle contraction, particularly on the forehead and around the eyes.
But what are the real virtues of this active ingredient? Let’s find out together.
What is Argireline?
Argireline is a synthetic peptide with anti-aging properties, known by the trade name acetyl hexapeptide-3. Peptides are short chains of amino acids, and Argireline is one of the first peptides to demonstrate efficacy against dynamic wrinkles. It works by influencing the communication between nerves and muscles, thereby reducing muscle contraction that contributes to wrinkle formation. In addition to this muscle-relaxing effect, Argireline also stimulates collagen production, which helps maintain smooth, wrinkle-free skin.
What active ingredients should be used with Argireline?
It has been suggested that combining Argireline with other peptides, such as tripeptide-10-citrulline or Matrixyl 3000, may enhance its effects. These tripeptides increase the permeability of Argireline, allowing it to penetrate deeper and reach the muscles responsible for wrinkles more effectively. Additionally, Argireline is often combined with hyaluronic acid (HA) for its moisturizing properties. Using a serum or cream enriched with HA together can enhance the moisturizing benefits and improve the overall appearance of the skin.
How does Argireline work on wrinkles?
Much like Botox, Argireline helps relax the muscles beneath the skin, reducing the appearance of wrinkles and giving skin a smoother, more youthful appearance. According to a study published in the International Journal of Cosmetic Science, Argireline can reduce wrinkle depth by up to 30% after 30 days of use. Unlike Botox, which is administered via injection, Argireline is often applied topically as a serum or cream, making it more accessible and less invasive. Additionally, Argireline works in a more subtle way by reducing muscle contraction without paralyzing the muscles.
How to integrate Argireline into your routine?
To take full advantage of the benefits of Argireline, it is advisable to use an oil, serum or cream containing this active ingredient. You can find Argireline in our TensioLift Serum , a 100% natural alternative to injections and invasive techniques. This serum, formulated in a clean and vegan way, targets wrinkles and expression lines thanks to its action on neuroreceptors. It contains Argireline® at a concentration of 10%, which effectively inhibits the transmission of nerve signals to the muscles.
To optimize the results, complete the application of the serum with a facial massage. This gesture promotes muscle relaxation and stimulates collagen production, helping to delay the signs of skin aging. The massage allows the active ingredients to penetrate more deeply while working on all areas affected by skin aging: frown lines, forehead wrinkles, nasolabial folds, and facial oval. You will find instructions for this massage technique via the QR code on the serum packaging or by email after your purchase.
(1) Blanes-Mira, C., Clemente, J., Jodas, G., Gil, A., Fernández-Ballester, G., Ponsati, B., ... & Pérez-Payá, E. (2002) . A synthetic hexapeptide (Argireline) with antiwrinkle activity. *International Journal of Cosmetic Science*, 24(5), 303-310.
(2) Wang, Y., Wang, M., Xiao, S., Pan, P., Li, P., & Huo, J. (2013). The anti-wrinkle efficacy of Argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study. *Journal of Cosmetic and Laser Therapy*, 15(2), 74-79.
(3) Borboni, P., & Porzio, S. (2014). Cosmeceuticals peptides. *Dermatology: From Pathogenesis to Treatment*, 153-164.
